Novel polyvalent virus vaccine
AssigneeGist-Brocades N.V.
InventorGosse Bijlenga
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Abstract
A polyvalent virus vaccine for immunization of warm-blooded animals comprising a mixture of a rabies virus, preferably rabies strain No. 675 deposited in the Czechoslovak National Collection of Type Cultures of the Institute of Hygiene and Epidemiology in Prague under No. CNCTC No. A 04/77, and a canine distemper virus, said mixture being substantially free of material emanating from more than one type of tissue cell used to propagate the viruses and a process for its preparation by infecting a suitable single cell system with a rabies virus strain, propagating the rabies virus, infecting the cell system with at least one canine distemper virus, propagating the viruses and separating the polyvalent vaccine from the propagation product.
Claims24
A process for the preparation of a polyvalent virus vaccine comprising a live rabies virus and a live canine distemper virus substantially free from material emanating from more than one type of tissue cell used to propagate the viruses comprising first propagating at least one living rabies virus in a single cell and then propagating at least one living canine distemper virus in the same single cell and preparing the polyvalent vaccine from the propagation product.
Dependencies are inferred from the claim text.