Diagnostic and therapeutic capsules and method of producing
AssigneeE. R. Squibb & Sons, Inc.
InventorsNabil A. Morcos, Thomas A. Haney, Paul W. Wedeking
Life of this patent
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Abstract
An article of manufacture comprising a pharmaceutical radioactive capsule formed essentially of a non-toxic, water soluble material adapted to being ingested and rapidly disintegrating on contact with fluids of the gastro-intestinal tract, and having a filler material supporting a pharmaceutically useful radioactive compound absorbable from the gastro-intestinal tract said filler material being supported by said capsule. And a method of filling a pharmaceutical radioactive capsule comprising providing filler material supporting a pharmaceutically useful radioactive compound and transporting said filler material carrying a pharmaceutically useful radioactive compound into the chamber of said capsule.
Claims10
An article of manufacture comprising, a pharmaceutical capsule formed essentially of a nontoxic, water soluble material adapted to being ingested and rapidly disintegrating on contact with fluids of the gastro-intestinal tract and a polyethylene glycol filler material having a pharmaceutically useful radioactive iodine and a reducing agent dispersed therein, said capsule having a central axis and an inner surface, said inner surface defining a volume within said capsule, said filler material being supported by said inner surface of said capsule,
- a major portion of said volume within said capsule containing said filler material, said filler material having a shape which is coextensive with the inner surface of said capsule, said filler material extending radially across the central axis of said capsule, said filler material containing a major portion of said radioactive iodine within the interior of said filler material, whereby said major portion of said radioactive compound does not contact said inner surface of said capsule.
A method of filling a pharmaceutical capsule having an inner surface defining a volume within said capsule, said capsule being formed essentially of a nontoxic, water soluble material adapted to being ingested and rapidly disintegrating on contact with fluids in the gastrointestinal tract comprising providing a polyethylene glycol filler material having a pharmaceutically useful radioactive iodine and a reducing agent dispersed therein and transporting said filler material into said capsule, whereby a major portion of said volume within said capsule is filled with filler material.
Dependencies are inferred from the claim text.