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US 4,342,751 AGranted
Majusculamide C
AssigneeEli Lilly and Company
InventorsRichard E. Moore, Jon S. Mynderse
Life of this patent
Estimating the term…
Abstract
Majusculamide C, a novel cyclic peptide compound which inhibits fungal plant pathogens, process for its preparation from a deep-water blue-green alga, Lyngbya majuscula, and process for inhibiting fungal plant pathogens with and fungicidal compositions containing majusculamide C.
Claims4
Majusculamide C, which is a white amorphous solid having these characteristics:
- (a) a molecular weight of approximately 984;
- (b) an empirical formula of about C.sub.50 H.sub.80 N.sub.8 O.sub.12 ;
- (c) a specific optical rotation, [.alpha]sub.D, of -96.degree. (c 2.5, CH.sub.2 Cl.sub.2);
- (d) an infrared spectrum as shown in the accompanying drawing;
- (e) an ultraviolet absorption spectrum in ethanol with absorption maxima at 278 nm (.epsilon. 1420) and 230 nm (.epsilon. 5900);
- (f) is soluble in solvents such as methanol, dichloromethane, and acetone, but is insoluble in water;
- (g) contains the structural sub-units 1a-1h:
- ##STR3## (h) appears to contain the sub-unit grouping:
- glycyl-N-methylisoleucylglycyl-N-methylvalyl-N,O-dimethyltyrosyl;
- and
- (i) the following tentative structure:
- ##STR4##
9 more elements
Dependencies are inferred from the claim text.