Use of snake venoms for treatment of neurological and related disorders
OwnerWilliam E. Haastinventor
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Abstract
The present invention provides stable compositions of matter including venoms and/or venom fractions extracted from various elapid and viperid snakes, the present compositions of matter having pharmacological activity and being further useful in treating the symptoms of neurological and other disorders, particularly disorders which are caused by malfunction of the immune mechanisms. The present compositions of matter generally include a post-synaptic component capable of binding to nicotinic acetylcholine receptors of cells, a pre-synaptic component capable of inhibition of acetylcholine release, and a viperid component considered to be stimulative of the immune system. Methods of preparation and use of the present compositions of matter are also disclosed.
Claims37
A composition of matter having pharmacological activity comprising in an administerable form at least one post-synaptic neurotoxin, at least one pre-synaptic neurotoxin, and at least one component capable of stimulating
A composition of matter having pharmacological activity and having therapeutic benefits in the treatment of the symptomology of progressive degenerative neurological diseases, the disease complex known as arthritis, viral infections and autoimmune disorders, comprising in an administrable form effective amounts of a post-synaptic neurotoxin obtained from the venom of an elapid snake, a pre-synaptic neurotoxin obtained from the venom of an elapid snake, and the venom obtained from a
A method of treatment of mammals suffering from progressive degenerative neurological disease comprising administering to the mammal a disease mitigating amount of a mixture comprised of at least one post-synaptic neurotoxin, at least one pre-synaptic neurotoxin, and at least one component capable of stimulating the immune mechanism thereof.
A method of treatment of mammals suffering from the disease complex referred to as arthritis including rheumatoid arthritis comprising administering to the mammal a disease mitigating amount of a mixture comprised of at least one post-synaptic neurotoxin, at least one
A method of treatment of mammals suffering from viral infections including herpes zoster, herpes genitalis and herpes simplex, autoimmune disorders, and hypertension, comprising administering to the mammal a disease mitigating amount of a mixture comprised of at least one post-synaptic neurotoxin, at least one pre-synaptic neurotoxin, and a
A composition of matter having pharmacological activity comprising in an administrable form at least one post-synaptic neurotoxin obtained from the venom of an elapid snake, a pre-synaptic neurotoxin obtained from the
Dependencies are inferred from the claim text.