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US 4,336,809 AGranted
Human and animal tissue photoradiation system and method
AssigneeBurleigh Instruments, Inc.
InventorWilliam G. Clark
Life of this patent
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AssigneeBurleigh Instruments, Inc.
InventorWilliam G. Clark
Estimating the term…
A tissue photoradiation system uses a hematoporphyrin or hematoporphyrin derivative dye in tissue to be irradiated and arranges a xenon ion laser 10 for simultaneous lasing. Deep blue light is produced at wavelengths of about 406-427 nanometers and red light at a wavelength of about 627 nanometers by using partially transmitting mirrors 12 and 13 arranged at opposite ends of the laser resonator. Mirror 12 has a coating 14 that substantially reflects blue light and partially transmits red light to produce a red light output, and the coating 15 of mirror 13 substantially reflects red light and partially transmits blue light producing a blue light output. The blue light output is transmitted to a diagnostic tissue irradiator 21 to illuminate the tissue and diagnose its condition. A transmission system using an optical fiber 25 delivers the red light to the tissue for treatment purposes. The red light is radiated out the side of an optical fiber region 30a to be directed into large area of tissue.
A tissue photoradiation system using a hematoporphyrin or hematoporphyrin derivative dye in tissue to be irradiated, said system comprising:
The method of photoradiation therapy which comprises simultaneously generating with a single laser radiation of at least two different wavelengths which excite malignant cells when a photosensitizer is present therein to cause flurorescence from at least one of said wavelengths and cytotoxic effects from at least another of said wavelengths therein, and delivering said radiation of each of said wavelengths to irradiate said cells.
Dependencies are inferred from the claim text.