US 4,331,592 A · Process for the preparation of carboxylic acid amides and peptides

Abstract

What is disclosed is a method of making a carboxylic acid amide, including a peptide, by reacting a compound having a free amino group with a compound having a free carboxy group in the presence of an anhydride of an alkane-phosphonic acid.

Claims3

Dependent claims

The method of making a carboxylic acid amide which comprises reacting a compound having a free amino group with a compound having a free carboxyl group in the presence of an anhydride of an alkane phosphonic acid.

Dependencies are inferred from the claim text.

Facts

Application

06/112,458Filed 16 Jan 1980

Priority

DE 290184318 Jan 1979

Granted

25 May 1982

Term ends

Not estimatedThe source records don’t support an estimate.

Classification11 codes

C07K 5/06026
And aliphatic: the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
C07D 231/50
Oxygen atom in position 3 or 5 and nitrogen atom in position 4: acylated on said nitrogen atom
C07D 333/38
With hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals,…:…
C07F 9/3895
Phosphonic acids [RP2]; Thiophosphonic acids ; [RP2]: pyrophosphonic acids; phosphonic acid anhydrides

Process for the preparation of carboxylic acid amides and peptides

Life of this patent

Abstract

Claims3

Process for the preparation of carboxylic acid amides and peptides

Life of this patent

Abstract

Claims3