Carbonate diester solutions of PGE-type compounds
AssigneeSyntex (U.S.A.) Inc.
InventorsCheng-Der Yu, Ursula Bruenner
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Abstract
Stable compositions of PGE-type compounds are achieved by dissolving those compounds in carbonate diester solvents which may contain water up to the solubility limit of the carbonate diester.
Claims10
A stable pharmaceutical composition comprising a PGE or PGE-type compound dissolved in a cyclic carbonate diester solvent which may contain water in an amount up to the solubility limit of water for the diester solvent encapsulated in a soft shelled gelatin capsule.
A method for preparing a stable soft-shelled gelatin capsule composition of PGE or PGE-type compounds which comprises dissolving at least one of said compounds in a cyclic carbonate diester solvent which may contain water in an amount up to the solubility limit of water in the diester solvent and adding the mixture to a soft-shelled gelatin capsule.
Dependencies are inferred from the claim text.