Method and apparatus for dynamic equilibrium electrophoresis
AssigneeThe Regents of the University of California
InventorPatrick H. O'Farrell
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Abstract
Novel method and apparatus for separating, purifying and/or concentrating ions in a mixture of different molecular species using a method of electrophoresis in the presence of a counterflowing carrier fluid are provided. By selecting the appropriate carrier fluid flow rate, magnitude of the current and varying separation characteristics in a separation chamber, one or more similarly charged species of ions can be segregated into separate or discrete equilibrium zones within the chamber.
Claims26
A method of segregating at least one species of desired ions in a separation chamber having longitudinally varying separation characteristics comprising the steps of:
- introducing said ions into said chamber;
- imparting said ions with a movement in a first direction by flowing a carrier fluid through said chamber;
- and
- applying an electric field across said chanber to simultaneously electrophorese said ions in a second direction counter to said first direction to segregate each of said species in an equilibrium zone within the chamber.
Dependencies are inferred from the claim text.