Process for producing 7-aminocephalosporanic acid
AssigneeSandoz Ltd.
InventorGerd Ascher
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Abstract
Novel Cephalosporin C derivatives, their production and their use in isolating Cephalosporin C from culture filtrates for subsequent conversion of 7-aminocephalosporanic acid.
Claims2
In a process for the preparation of 7-ACA or a protected derivative thereof from cephalosporin C, which comprises protecting the free amino group in the 7-adipamyl side chain and deacylating the resulting protected cephalosporin C, the improvement which comprises reacting the free amino group in the 7-adipamyl side chain with a compound of the formula III ##STR7## wherein R.sub.2 and R.sub.3 each independently represent hydrogen, nitro, cyano or lower alkoxy carboxyl and
- R.sub.4 is lower alkyl.
Dependencies are inferred from the claim text.