Vehicle composition containing 1-substituted azacycloalkan-2-ones
AssigneeNelson Research & Development Company
InventorVithal J. Rajadhyaksha
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Abstract
Compositions useful for carrying physiologically active agents such as therapeutic agents through skin and other body membranes comprising the agent and an effective, non-toxic amount of a compound having the structural formula ##STR1## wherein R' is H or a lower alkyl group, m is 3-7, N is 0-17 and R is --CH.sub.3, phenyl or substituted phenyl or ##STR2## with the proviso that if m is 3 and R is --CH.sub.3, then n is not 0-6.
Claims11
A composition useful for topically administering a physiologically active agent to a human or animal comprising an effective amount of a physiologically active agent and a nontoxic, effective penetrating amount of a compound having the structural formula ##STR31## wherein n is 0-11 and R' is H or a lower alkyl group having 1-4 carbon atoms.
A composition comprising an effective amount of a physiologically active agent and an effective, penetrating amount of a compound having the structural formula ##STR32## where R' is H or a lower alkyl group having 1-4 carbon atoms, n is 0-17 and R is --CH.sub.3 or ##STR33## where R" is H or halagen.
A composition for topically administering a physiologically active agent to a human or animal comprising an effective amount of a physiologically active agent and a non-toxic, effective penetrating amount of 1-n-dodecylazacycloheptan-2-one.
A composition comprising an effective amount of physiologically active agent and an effective, penetrating amount of 1-n-dodecylazacycloheptan-2-one.
Dependencies are inferred from the claim text.