Back to results
US 4,310,519 AGranted
Novel substances and process for their production
AssigneeMerck & Co., Inc.
InventorsGeorge Albers-Schonberg, Hyman Wallick, Robert E. Ormond, Thomas W. Miller, Richard W. Burg
Life of this patent
Estimating the term…
Abstract
Novel compounds are produced by the fermentation of a nutrient medium with the previously undescribed microorganism Streptomyces avermitilis. They may be isolated by solvent extraction and chromatographic fractionation techniques. The compounds, which are described generically as C-076 have significant parasiticidal activity. The compounds may be included in compositions for the oral or parenteral administration to animals for the treatment of parasitic infections.
Claims14
A compound having the formula:
- ##STR3## wherein R is:
- ##STR4## and wherein the broken line indicates a single or a double bond;
- R.sub.1 is hydroxy and is present only when said broken line indicates a single bond;
- R.sub.2 is iso-propyl or sec-butyl;
- and
- R.sub.3 is methoxy or hydroxy.
3 more elements
Dependencies are inferred from the claim text.