Back to results
US 4,309,553 AGranted
Aldehydes and ketones containing a 4-(monoalkylamino)-benzoyl substituent
AssigneeAmerican Cyanamid Company
InventorRobert G. Shepherd
Life of this patent
Estimating the term…
Abstract
This disclosure describes novel aldehydes and ketones containing a 4-(monoalkylamino)phenyl moiety, derivatives and salts thereof, useful as hypolipidemic and antiatherosclerotic agents.
Claims8
A compound selected from the group consisting of those of the formula:
- ##STR6## wherein R.sub.1 is a straight chain or branched alkyl group of the formula C.sub.n H.sub.2n+1 wherein n is an integer from 8 to 19, inclusive;
- R.sub.3 is selected from the group consisting of hydrogen, alkyl having up to 6 carbon atoms, lower alkanoy-oxymethyl, phenyl, and phenyl lower alkyl;
- Z is a divalent radical selected from the group consisting of those of the formulae:
- ##STR7## wherein R.sub.4 is hydrogen or alkyl having up to 4 carbon atoms and R.sub.5 is hydrogen, carboxy, carboxymethyl, hydroxymethyl or alkyl having up to 3 carbon atoms;
- and the pharmacologically acceptable acid-addition and cationic salts thereof.
2 more elements
p-Hexadecylaminobenzaldehyde cycloethylene ketal.
p-Hexadecylaminoacetophenone cycloethylene ketal.
p-Hexadecylamino-2-oxyacetophenone cycloethylene ketal.
p-Hexadecylaminobenzaldehyde cycloethylene hemithioketal.
p-Hexadecylaminoacetophenone cycloethylene hemithioketal.
p-Hexadecylaminobenzaldehyde 1,3-cyclopropylene thioketal.
Dependencies are inferred from the claim text.