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AssigneeBattelle-Institut e.V.
InventorsHelmut Heide, Eva Poeschel, Ulrich Roth
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An implantable bone replacement material (body) based on completely or partially resorbable particles incorporated in a matrix material. The particles are composed of bioactive sintered calcium phosphate ceramic material having a CaO:P.sub.2 O.sub.5 composition ratio between 3:1 and 4:1. The replacement material (body) consists of a metal containing calcium phosphate ceramic material in the form of a monolayer of particles in the peripheral areas of the material (body) which serve as interfaces to the body tissue. The metal is compatible with body tissue. The ceramic particles have a size range between about 500 .mu.m and a few millimeters. The calcium phosphate particles are located so that they lie exposed on the upper surface of the material (body). Other embodiments and processes are also disclosed.
In an implantable bone replacement material based on completely or partially resorbable particles incorporated in a matrix material, the particles being made of bioactive sintered calcium phosphate ceramic material having a CaO:P.sub.2 O.sub.5 composition ratio between 3:1 and 4:1, the improvement comprised of the matrix material consisting of a metal containing calcium phosphate ceramic material in the form of a monolayer of particles in the peripheral areas of the metal which serve as interfaces to the body tissue, the metal being compatible with body tissue, the ceramic particles having a size range between about 500 .mu.m and a few millimeters, the calcium phosphate particles being located so that they are exposed on the outer surface on the metal, and the metal being noncomposite in structure and being nonlayered in that there are no distinct boundaries between any regions of the metal.
In an implantable bone replacement material based on completely or partially resorbable particles incorporated in a matrix material, the particles being made of bioactive sintered calcium phosphate ceramic material having a CaO:P.sub.2 O.sub.5 composition ratio between 3:1 and 4:1, the improvement comprising the calcium phosphate ceramic is incorporated in a matrix material which is metal, the metal being compatible with body tissue, the ceramic being in the form of uniformly distributed particles having a size range between 20 and 100 .mu.m, the volume of the calcium phosphate ceramic in the metal being between 10 and 30 volume percent, and the metal being noncomposite in structure and being nonlayered in that there are no distinct boundaries between any regions of the metal.
In an implantable bone replacement material based on completely or partially resorbable particles incorporated in a matrix material, the particles being made of bioactive sintered calcium phosphate ceramic material having a CaO:P.sub.2 O.sub.5 composition ratio between 3:1 and 4:1, the improvement comprising the matrix material consisting of a solid core region of metal, and a surface region of the metal having fine-grained inclusions of calcium phosphate ceramic material, the coating having been applied to the core by spraying, the metal compatible body tissue, the surface region of the metal containing between 10 and 40 volume percent of the calcium phosphate ceramic material, and the metal being noncomposite in structure and being nonlayered in that there are no distinct boundaries between any regions of the metal.
Dependencies are inferred from the claim text.