Method and composition for treating inflammatory disorders
AssigneeVerronmay Limited
InventorDavid F. Horrobin
Life of this patent
Estimating the term…
Abstract
Compositions and use of .gamma.-linolenic acid and related materials with (i) zinc, .beta.-lactam antibiotics or other materials enhancing physiological 1-series PG synthesis and/or (ii) colchicine, Vinca alkaloids or other materials enhancing physiological synthesis of thromboxane A2, for treatment of inflammatory disorders.
Claims37
A pharmaceutical composition useful for the treatment of inflammatory disorders comprising:
- (a) an effective amount of .gamma.-linolenic acid or physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or physiologically functional derivative thereof, and (b) an effective, conjoint amount of another material enhancing the synthesis or action of thromoboxane A2, alone or in an acceptable pharmaceutical vehicle.
A pharmaceutical composition useful for the treatment of inflammatory disorders comprising:
- (a) an effective amount of .gamma.-linolenic acid or physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or physiologically functional derivative thereof, and (b) an effective, conjoint amount of a material selected from colchicine, vinblastine, vincristine, and other Vinca alkaloids, griseofulvin, amantadine, melatonin, and interferon, alone or in an acceptable pharmaceutical vehicle.
A pharmaceutical composition useful for the treatment of inflammatory disorders comprising (a) an effective amount of .gamma.-linolenic acid or physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or physiologically functional derivative thereof, and (b) an effective, conjoint amount of a material selected from penicillamine, phenformin and levamisole, alone or in an acceptable pharmaceutical vehicle.
A method of treating inflammation, comprising administering to a person suffering therefrom an effective amount of .gamma.-linolenic acid or a physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or a physiologically functional derivative thereof, and an effective conjoint amount of a material influencing the 1-series/2-series PG balance in the body in factor of the 1-series PG's.
A method of treating inflammation, comprising administering to a person suffering therefrom an effective amount of .gamma.-linolenic acid or a physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or a physiologically functional derivative thereof, and an effective conjoint amount of a material selected from physiologically assimilible zinc, penicillamine, phenformin, levamisole, or a .beta..gamma.-lactam antibiotic.
A method of treating inflammation, comprising administering to a person suffering therefrom an effective amount of .gamma.-linolenic acid or a physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or a physiologically functional derivative thereof and an effective conjoint amount of a material enhancing synthesis or action of thromboxane A2.
A method of treating inflammation, comprising administering to a person suffering therefrom an effective amount of .gamma.-linolenic acid or a physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or a physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or a physiologically functional derivative thereof and an effective conjoint amount a material selected from colchicine, vinblastine, vincristine and other Vinca alkalodis, griseofulvin, amantadine, melatonin, and interferon.
A method of treating inflammation, comprising administering to a person suffering therefrom (1) an effective amount of .gamma.-linolenic acid or a physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or physiologically functional derivative thereof, (2) an effective conjoint amount of physiologically assimilable zinc, penicillamine, phenformin, levamisole, or a .beta.-lactam antibiotic, and (3) an effective conjoint amount of a material selected from colchicine, vinblastine, vincristine and other Vinca alkaloids, griseofulvin, amantadine, melatonin, and interferon.
Dependencies are inferred from the claim text.