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US 4,309,414 AGranted
Antiinflammatory analgesic gelled ointment
AssigneeKowa Company, Ltd.
InventorsToshio Inagi, Toyojiro Muramatsu, Hidetaka Nagai
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Abstract
An antiinflammatory analgesic gelled ointment is disclosed which comprises indomethacin, a medium consisting of a glycol, alcohol and water, a gelling agent selected from cellulose and a carboxyvinyl polymer which has been neutralized with an amine, and water sufficiently enough to make up the balance. Such gelled ointment has an excellent antiinflammatory activity.
Claims4
An anti-inflammatory analgesic ointment comprising:
- indomethacin in the range of from 0.5-1.5% by weight;
- a medium consisting of a glycol in the range of from 5-35% by weight, an alcohol in the range of from 10-50% by weight, and water in the range of 30-55% by weight and a gelating agent in an amount of 0.5 to 5% by weight selected from the group consisting of a cellulose compound and a carboxyvinyl polymer which has been neutralized with an amine;
- and adjuvant in the range of from 0.5% to 5% by weight selected from the group consisting of a C.sub.1 -C.sub.5 alcohol ester of a C.sub.4 -C.sub.14 monocarboxylic acid and a C.sub.1 -C.sub.3 alcohol diester of a C.sub.4 -C.sub.10 dicarboxylic acid;
- and water in an amount sufficient to make up the balance of the ointment, said ointment being adjusted to the pH of 5.5 to 7.5.
1 more element
Dependencies are inferred from the claim text.