Method of producing immune response by administering polymeric composition
AssigneeMonsanto Company
InventorsJoseph E. Fields, Samuel S. Asculai, John H. Johnson
Life of this patent
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Abstract
The disclosure relates to a method of producing an immune response in a warm-blooded animal comprising administering to said animal from about 0.1 to about 100 mg/Kg of body weight of a composition selected from the group consisting of a copolymer of olefin monomer and polycarboxylic anhydride having an average molecular weight of from about 300 to about 1500 in which said copolymer is derivatized to contain (a) half-amide, half-carboxyl acid groups and (b) imide groups in which said imide groups comprise from about 5% to about 40% by weight of said derivatized groups, and the pharmaceutically acceptable cationic salt derivatives of said derivatized copolymers.
Claims7
The method of regulating an immune response in a warm-blooded animal suffering from an immune reaction comprising administering to said animal an effective immune regulatory amount of a composition selected from the group consisting of a copolymer of at least one olefin monomer having from 2 to about 4 carbon atoms and at least one .alpha.,.beta.-unsaturated polycarboxylic anhydride having from 4 to about 6 carbon atoms, having an average molecular weight of from about 300 to about 1500, and derivatized to contain both (a) half-amide, half-carboxyl acid groups and (b) imide groups in which said imide groups comprise from about 5% by weight to about 40% by weight of said derivatized groups, and the pharmaceutically acceptable cationic salt derivatives of said derivatized copolymer.
Dependencies are inferred from the claim text.