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US 4,309,342 AGranted
Antibacterial peptides
AssigneeAbbott Laboratories
InventorsDaniel T. Chu, Jerry R. Martin, Alford M. Thomas
Life of this patent
Estimating the term…
Abstract
It has been found that dipeptides containing a 3-fluoro-D-alanine N-terminus are powerful antibacterials and produce a highly useful synergistic effect with antibiotics.
Claims8
A dipeptide of the formula ##STR2## wherein the shown aminoacid is in the D-configuration, R is hydrogen or an easily removable, protective group, R' is hydrogen or deuterium and R" is a protein derived aminoacid in the L-configuration, or the corresponding loweralkyl esters, or a nontoxic acid addition salt thereof.
Dependencies are inferred from the claim text.