Thromboxane A.sub.2 analogues
AssigneeResearch Corporation
InventorsKyriacos C. Nicolaou, Ronald L. Magolda
Life of this patent
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Abstract
Stable biologically active thromboxane A.sub.2 analogues having the formula ##STR1## wherein R.sup.1 is OR.sup.3, where R.sup.3 represents hydrogen or a pharmaceutically acceptable cation or lower alkyl group; or R.sup.1 is NR.sup.4 R.sup.5 where R.sup.4 and R.sup.5 are the same or different substituents selected from the group consisting of hydrogen and lower alkyl group; and R.sup.2 is hydrogen or an --OH group.
Claims12
Stable biologically active thromboxane A.sub.2 analogues having the formula ##STR15## wherein R.sup.1 is OR.sup.3, where R.sup.3 represents hydrogen or a pharmaceutically acceptable cation or lower alkyl group;
- or
- R.sup.1 is NR.sup.4 R.sup.5 where R.sup.4 and R.sup.5 are the same or different substituents selected from the group consisting of hydrogen and lower alkyl group;
- and
- R.sup.2 is hydrogen or an --OH group.
Dependencies are inferred from the claim text.