1,2,3,4-Tetrahydro-2-piperazinyl-naphthalenes for treating hypertension

A compound of formula ##STR39## wherein R.sub.1 is hydroxy, alkoxy of 1 to 4 carbon atoms, alkanoyloxy of 1 to 20 carbon atoms or a ##STR40## group, wherein R.sub.4 and R.sub.5 may independently be hydrogen, fluorine, chlorine, bromine, iodine, alkyl of 1 to 4 carbon atoms or alkoxy of 1 to 4 carbon atoms or, when bonded to adjacent carbon atoms, R.sub.4 and R.sub.5 together may be a methylenedioxy group,

• R.sub.2 and R.sub.3 may independently be hydrogen, hydroxy, alkoxy of 1 to 4 carbon atoms, alkanoyloxy of 1 to 20 carbon atoms or a ##STR41## group, or when bonded to adjacent carbon atoms R.sub.1 and R.sub.2 together may be a methylenedioxy group, A is
• (a) a ##STR42## group, wherein X, Y and Z may independently be hydrogen, hydroxy, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, a ##STR43## group, fluorine chlorine, bromine, iodine, CF.sub.3, alkylthio of 1 to 4 carbon atoms or alkanoylthio of 1 to 20 carbon atoms, or when bonded to adjacent carbon atoms X and Y together may be methylenedioxy,
• D is O or S
• (b) a ##STR44## group, (c) a five or six membered ring of formula ##STR45## wherein V is either divalent and signifies O, S, NH or CH.sub.2 or trivalent and signifies N or CH,
• W is a saturated or unsaturated alkylene chain of 2 or 3 carbon atoms
• and ring B can contain 1, 2 or 3 double bonds, or a pharmaceutically acceptable acid addition salt thereof.