Nanaomycin B and therapeutic compositions containing same
AssigneeThe Kitasato Institute
InventorsSatoshi Omura, Haruo Tanaka, Juichi Awaya, Toju Hata
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AssigneeThe Kitasato Institute
InventorsSatoshi Omura, Haruo Tanaka, Juichi Awaya, Toju Hata
Estimating the term…
The present invention relates to new compound designated as nanaomycin B represented by general formula: ##STR1## Nanaomycin B is a quinone type and is active on mycoplasma, Gram-positive bacteria and trycophyton. This compound is useful as a medicament for infectious diseases of humans and animals caused by a parasite of trichophyton or mycoplasma etc. The acute toxicity (LD.sub.50, intra-penetrial injection) in mice of this compound is 169 mg/Kg. Nanaomycin B is produced by fermentation in which a nanaomycin-producing strain belonging to the genus Streptomyces is cultured in a medium under aerobic conditions and the accumulated nanaomycin B in the cultured broths is recovered therefrom.
A new compound nanaomycin B represented by general formula:
Dependencies are inferred from the claim text.