.beta.-Lactones of 2-hydroxy-cyclopentane-carboxylic acids
AssigneeRoussel Uclaf
InventorsJean Buendia, Michel Vivat, Laurent Taliani
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AssigneeRoussel Uclaf
InventorsJean Buendia, Michel Vivat, Laurent Taliani
Estimating the term…
Novel .beta.-lactones of 2-hydroxy-cyclopentane-carboxylic acids of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen and methyl and R.sub.2 is selected from the group consisting of --CH.sub.2 --O--CH.sub.2 --CH.sub.3 and --X--Ar, X is selected from the group consisting of --O-- and --CH.sub.2 --, Ar is an optionally substituted member selected from the group consisting of thienyl, thiazolyl, phenyl and thiadiazolyl, the optional substituents being at least one member selected from the group consisting of halogen and --CF.sub.3 and the wavy lines indicate that the groups may be in the .alpha.,.beta. or .beta.,.alpha.-positions or mixtures thereof having hypotensive activity and their preparation.
A compound having the formula ##STR32## wherein R.sub.3 is selected from the group consisting of CH.sub.2 --OH, formyl and .alpha.-tetrahydropyranyloxymethyl.
Dependencies are inferred from the claim text.