Prolylphenylalanylarginine derivatives, process for producing same and method for measuring activity of enzymes using same
AssigneeTorii & Co., Ltd.
InventorsSetsuro Fujii, Mamoru Sugimoto, Takashi Yaegashi
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Abstract
A prolylphenylalanylarginine derivative represented by the formula, ##STR1## wherein R.sub.1 represents hydrogen or benzoyl; R.sub.2 represents naphthyl or 6-bromo-2-naphthyl. The above compound is useful as an excellent substrate for various enzymes, such as trypsin, plasmin, kallikrein, urokinase, Clesterase and the like. Accordingly, the activity of enzymes can be measured by use of said compound as a substrate.
Claims5
A prolylphenylalanylarginine derivative represented by the formula, ##STR11## wherein R.sub.1 represents hydrogen or benzoyl;
- and R.sub.2 represents naphthyl or 6-bromo-2-naphthyl.
L-prolyl-L-phenylalanyl-L-arginine 1-naphthyl ester.
Benzoyl-L-prolyl-L-phenylalanyl-L-arginine 1-naphthyl ester.
L-prolyl-L-phenylalanyl-L-arginine 6-bromo-2-naphthyl ester.
Benzoyl-L-prolyl-L-phenylalanyl-L-arginine 6-bromo-2-naphthyl ester.
Dependencies are inferred from the claim text.