Process for the purification of isoleucine
AssigneeSociete d'Assistance Technique pour Produits Nestle S.A.
InventorsRaymond Bertholet, Pierre Hirsbrunner
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Abstract
From a mixture of isoleucine and leucine in a ratio by weight of at least 3:7, the isoleucine is precipitated in an anhydrous solvent, particularly methyl ethyl ketone, using concentrated sulphuric acid. The precipitate is separated and freed from sulphuric acid, for example by neutralisation with barium hydroxide after elimination of the solvent. Industrial production of marketable isoleucine from a mixture still containing leucine.
Claims7
A process for the purification of isoleucine from a mixture of leucine and isoleucine comprising treating said mixture in anhydrous aliphatic ketone with sulphuric acid in a quantity of from about 0.5 to 1 times the molar equivalence of the mixture to form a precipitate, separating the precipitate and freeing the precipitate from sulphuric acid.
Dependencies are inferred from the claim text.