Process for the preparation of methyl 2,2-dimethyl, -3-(2'methyl-propenyl)-cyclopropane-1,1-dicarboxylate
AssigneeRoussel Uclaf
InventorsJacqueline Ficini, Jean-Pierre Genet
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Abstract
Novel penten-2-yl derivatives of the formula in the trans form ##STR1## wherein R is selected from the group consisting of hydrogen and acetyl and to a novel process for the preparation of methyl 2,2-dimethyl-3-(2'-methyl-propenyl)-cyclopropane-1,1-dicarboxylate which is an intermediate for chrysanthemic acid.
Claims4
A process for the preparation of methyl 2,2-dimethyl-3-(2'-methyl-propenyl)-cyclopropane-1,1-dicarboxylate comprising reacting a cis compound of the formula ##STR9## with an acetylation agent to obtain a monoacetate of cis form of the formula ##STR10## reacting the latter with a sodium malonate derivative of the formula ##STR11## in the presence of a palladium (o) complex in an organic solvent to obtain a compound in the trans form of the formula ##STR12## reacting the latter with an acetylation agent to obtain a compound in the trans form of the formula ##STR13## and reacting the latter with an alkali metal hydride in an organic solvent and then with a palladium (o) complex to obtain the said desired compound.
Dependencies are inferred from the claim text.