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US 4,307,113 AGranted
Anthranilic acid derivatives
AssigneeSandoz Ltd.
InventorPaul L. Anderson
Life of this patent
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Abstract
Agents for lowering glucose levels in blood having the formula: ##STR1## wherein R.sub.o is bromo, chloro, fluoro, nitro or trifluoromethyl, R is hydrogen, C.sub.1-6 alkyl or C.sub.2-18 alkanoyl, and R.sub.1 is hydrogen or C.sub.1-12 alkyl, and the non-toxic, pharmaceutically acceptable salts thereof.
Claims28
A method of treating diabetes by lowering the glucose levels in blood plasma comprising administering to a diabetic host a therapeutically effective amount of a compound of formula I:
- ##STR16## wherein R.sub.o is bromo, chloro, fluoro, nitro or trifluoromethyl,
- R is hydrogen, C.sub.1-6 alkyl or C.sub.2-18 alkanoyl, and
- R.sub.1 is hydrogen or C.sub.1-12 alkyl,
- or a pharmaceutically acceptable simple or acid addition salt thereof, said therapeutically effective amount being an amount effective for the treatment of diabetes.
1 more element
Dependencies are inferred from the claim text.