Sulfonated bis(naphthoxy)alkanes as dental plaque barriers
AssigneeJohnson & Johnson Products, Inc.
InventorCarl J. Buck
Life of this patent
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Abstract
Compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated bis(naphthoxy)alkanes and the pharmaceutically acceptable salts thereof. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.
Claims5
A sulfonated alpha, omega-bis(naphthoxy)alkane having a structure selected from the group consisting of structure (A), ##STR6## and structure (B), ##STR7## and structure (C), ##STR8## wherein R is hydrogen or a linear or branched alkyl having from 1 to 20 carbon atoms, n is an integer from 2 to 12, and M is selected from the group consisting of hydrogen, lithium, sodium, potassium, calcium, magnesium, zinc, aluminum, ammonium and the substituted ammonium ions derived from pharmaceutically acceptable organic amines;
- provided that R and n are so selected that the weight percent of (SO.sub.3 M) the groups is in the range of about 18% to 35%.
An oral hygiene composition comprising an effective amount for preventing attachment of dental plaque to teeth of a sulfonated alpha, omega-bis(naphthoxy)alkane having a structure selected from the group consisting of structure (A), ##STR9## and structure (B), ##STR10## and structure (C), ##STR11## wherein R is hydrogen or a linear or branched alkyl having from 1 to 20 carbon atoms, n is an integer from 2 to 12, and M is selected from the group consisting of lithium, sodium, potassium, calcium, magnesium, zinc, aluminum, hydrogen, ammonium, and substituted ammonium ions derived from pharmaceutically acceptable organic amines, provided further that R and n are so selected that the weight percent of the SO.sub.3 M groups is between about 18 and about 35, in a pharmaceutically acceptable oral hygiene vehicle compatible with said compound of structure (A), (B) or (C).
Dependencies are inferred from the claim text.