Topical treatment of aphthous stomatitis

A method of treating aphthous stomatititis, affecting mucous membranes of the mouth lips cheeks and gums of the oral cavity comprising topical application of tape dosage forms containing a therapeutically effective minor amount of at least one topically effective antibiotic, antibacterial, antimicrobial, antiinfective or antiviral active agent to the affected area wherein the active agent is localized in an area of the tape selected from either (a) the central portion of the tape, the adhesive surfaces of which form an adhesive border around the active agent, or (b) the adhesive layer of the tape.