Method and apparatus for storing and preparing cryopreserved blood
AssigneeRensselaer Polytechnic Institute
InventorAllen Zelman
Life of this patent
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Abstract
A bag for containing blood or blood components comprising a closed container made of material which is permeable to a cryoprotective agent, such as glycerol, which may be added to the blood or blood components directly through the permeable walls of the blood bag. The cryoprotective agent protects the blood or blood components when the blood is frozen for storage and the cryoprotective agent can thereafter be removed through the permeable walls of the container without contaminating the blood therein. An apparatus and process is also disclosed for the cryoprotective agent to be added or removed from the blood bag using electric current, hydrostatic pressure, centrifugal force or osmosis.
Claims8
A bag for containing a mixture of blood or blood components and a cryoprotective agent and, in particular red blood cells, comprising a container having at least one port for the entry and exit of blood or blood components and at least one semi-permeable wall portion which is permeable to the cryoprotective agent whereby the cryoprotective agent can be added to or removed from the container through the wall portion, the wall portion being made of dialysis membrane of the type used in hemodialysis.
A bag for containing a mixture of blood or blood components and a cryoprotective agent and, in particular, red blood cells, comprising a container having at least one port for the entry and exit of blood or blood components and at least one semi-permeable wall portion which is permeable to the cryoprotective agent and whereby the cryoprotective agent can be added to or removed from the container through the wall portion, an electro-osmosis membrane connected to an exterior of at least one wall portion whereby the cryoprotective agent can be added to or removed from the closed container through said at least one wall portion and said electro-osmosis membrane by the passage of an electric current through said at least one wall portion and electro-osmosis membrane.
Dependencies are inferred from the claim text.