4-Substituted 3,5-morpholinediones
AssigneeMcNeil Laboratories, Incorporated
InventorMichael J. Umen
Life of this patent
Estimating the term…
Abstract
Novel (2-amino-2-oxoethoxy)acetic acid compounds and antisecretory compositions and methods employing (2-amino-2-oxoethoxy)acetic acid compounds are disclosed. The (2-amino-2-oxoethoxy)acetic acid compounds are also useful as cardiotonic agents and as calcium binding agents; certain of the compounds are also useful for their calcium transport properties. Novel 4-substituted 3,5-morpholinediones intermediates in the preparation of certain of the (2-amino-2-oxoethoxy)acetic acid compounds and further useful as antisecretory agents are also disclosed.
Claims3
A compound represented by the formula ##STR26## wherein Y is a piperidine or substituted piperidine radical represented by ##STR27## wherein each Ar independently is phenyl, trifluoromethylphenyl, halo-substituted-phenyl, lower alkyl-substituted-phenyl or lower alkoxy-substituted-phenyl;
- m is an integer of from 2 to 6;
- and acid addition salts.
Dependencies are inferred from the claim text.