Method for recovering myeloperoxidase and pharmaceutical composition containing myeloperoxidase as major constituent
AssigneeThe Green Cross Corporation
InventorsEichi Hasegawa, Takashi Kobayashi
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Abstract
Myeloperoxidase can be separated and recovered from a supernatant liquid of an aqueous dispersion of a disintegration product of human myelogenous leukocytes, which dispersion has been admixed with at least one member selected from the group consisting of manganese salts and protamine sulfate. The recovered myeloperoxidase in combination with an alkali metal halide can be used as a pharmaceutical composition effective against microorganisms deficient or diminished in catalase synthesizing activity.
Claims8
A method for separating myeloperoxidase, which comprises admixing an aqueous suspension of a disintegration product of human myelogenous leukocytes with at least one member selected from the group consisting of manganese salts, and protamine sulfate and then separating and recovering myeloperoxidase from the supernatant liquor.
Dependencies are inferred from the claim text.