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US 4,305,952 AGranted
8-Aryl-5,6,7,8-tetrahydropyrazolo(3,4-B)(1,4)-diazepine-1H, 4H-5,7-diones, and medicaments containing these
AssigneeHoechst Aktiengesellschaft
InventorsGerhard Rackur, Irmgard Hoffmann
Life of this patent
Estimating the term…
Abstract
8-Aryl-5,6,7,8-tetrahydropyrazolo(3,4-b)(1,4)diazepine-1H,4H-5,7-diones of the formula ##STR1## in which R.sub.1 through R.sub.5 are as defined in the specification, and medicaments containing these having an anxiolytic action.
Claims6
An 8-Aryl-5,6,7,8-tetrahydropyrazolo(3,4-b) (1,4)diazepine-1H,4H-5,7-dione of the formula ##STR16## in which R.sub.1 and R.sub.2 are identical or different and represent each a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms;
- or one of the radicals R.sub.1 or R.sub.2 may also be a benzyl or phenyl group;
- R.sub.3 is a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms;
- or an alkyl group substituted by an alkoxy group having from 1 to 6 carbon atoms, or a dialkylamino group having from 2 to 12 carbon atoms, or a cycloalkyl group having 3 to 6 carbon atoms;
- or an alkenyl or alkinyl group having from 2 to 6 carbon atoms;
- a cycloalkyl group having from 3 to 6 carbon atoms;
- or a carbalkoxy group having from 2 to 6 carbon atoms;
- R.sub.4 is a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms, a phenyl group, a hydroxy group an alkoxy group having from 1 to 6 carbon atoms, a carbalkoxy group having from 2 to 6 carbon atoms, an acyl group having from 2 to 6 carbon atoms, an amino group, an alkylamino group having from 1 to 7 carbon atoms or a dialkylamino group having from 2 to 12 carbon atoms, or a carbamoyl group, or a carbamoyl carrying on the amino group thereof an alkyl group having from 1 to 6 carbon atoms or a dialkyl group having from 2 to 12 carbon atoms;
- R.sub.5 is a phenyl group, a phenyl group being mono- or bisubstituted by methyl, Cl, Br, F, nitro, cyano or trifluoromethyl, or a 2-pyridyl group.
5 more elements
Dependencies are inferred from the claim text.