N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones
AssigneeMead Johnson & Company
InventorsDavis L. Temple, Jr., Joseph P. Yevich, Walter G. Lobeck, Jr.
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Abstract
2-[4-[4-(7,9-Dioxo-8-azaspiro[4.5]decan-8-yl)butyl]-1-piperazinyl]pyridine- 3-carbonitrile, 2-[4-[4-(7,9-dioxo-8-azaspiro-[4.5]decan-8-yl)butyl]-3-methyl-1-piperaziny l]pyridine-3-carbonitrile and 8-[4-[4-(3-methoxy-2-pyridinyl)-1-piperazinyl]butyl]-8-azaspiro-[4.5]decan e-7,9-dione are psychotropic compounds.
Claims7
A compound selected from the group consisting of those having the formula ##STR11## and the pharmaceutically acceptable acid addition salts thereof wherein R.sup.1 and R.sup.2 are selected from the group consisting of hydrogen and methyl, and R.sup.3 is cyano.
The compound of claim 1, 2-[4-[4-(7,9-dioxo-8-azaspiro[4.5]decan-8-yl)butyl]-1-piperazinyl]pyridine -3-carbonitrile or a pharmaceutically acceptable acid addition salt thereof.
Dependencies are inferred from the claim text.