Back to results
US 4,305,940 AGranted
Benzamides with local anaesthetic and antiarrhythmic activity, salts, and method of preparation thereof and pharmaceutical compositions therefrom
AssigneeB.B.R. Boehringer Biochemia Robin S.p.A.
InventorGiuseppe Quadro
Life of this patent
Estimating the term…
Abstract
Benzamides of formula I ##STR1## are described, in which R=CH.sub.3, Cl or COOCH.sub.3 ; R' is a member selected from the group of dialkylamine, pyrrolidine, piperidine, and morpholine radicals. CH.sub.2 R' is in position ortho, meta, or para with respect to the carbonyl group; and their salts thereof with pharmaceutically acceptable acids are described. The novel compounds exhibit local anaesthetic and antiarrhythmic activity.
Claims16
A benzamide of formula I ##STR16## wherein R=CH.sub.3, Cl or COOCH.sub.3 ;
- R' is a member selected from the group of dialkylamine, pyrrolidine, piperidine, and morpholine radicals,
- CH.sub.2 R' is in position ortho, meta, or para with respect to the carbonyl group;
- and salts thereof with a pharmaceutically acceptable acid.
Dependencies are inferred from the claim text.