3-Aminosydnonimines, their preparation and use

A compound which, in its free-base form, is a pharmacologically-active and physiologically-acceptable 3-amino-syndnonimine of the formula ##STR17## wherein R.sup.1 is --H or halo;

• R.sup.2 is --H, --NO, --COR.sup.3 or SO.sub.2 R.sup.4 ;
• R.sup.3 is --H;
• optionally-substituted aliphatic hydrocarbyl having from 1 to 6 carbon atoms and any substituent of which is alkoxy with from 1 to 6 carbon atoms or carbocyclic aryloxy with from 6 to 12 carbon atoms;
• cycloaliphatic hydrocarbyl having from 5 to 8 ring carbon atoms;
• optionally-substituted carbocyclic aryl with from 6 to 12 ring carbon atoms and 0, 1, 2 or 3 substituents, any of which is, independently, halo, alkyl with from 1 to 4 carbon atoms or alkoxy with from 1 to 4 carbon atoms;
• araliphatic hydrocarbyl with from 7 to 13 carbon atoms;
• alkoxy with from 1 to 6 carbon atoms;
• carbocyclic aryloxy with from 6 to 12 ring carbon atoms;
• heteroaryl with 5 or 6 ring members, at least 2 of which are carbon atoms, at most one of which is a sulfur atom, at most one of which is an oxygen atom and at most three of which are nitrogen atoms, and wherein any ring member is a carbon atom, a sulfur atom, an oxygen atom or a nitrogen atom;
• or alkoxycarbonyl with from 2 to 7 carbon atoms;
• A is ##STR18## m is 1 or 2;
• and R.sup.4 is aliphatic hydrocarbyl with from 1 to 6 carbon atoms;
• optionally-substituted carbocyclic aryl with from 6 to 12 ring carbon atoms, any subtituent of which is methyl or chloro;
• or dialkylamino, each alkyl of which has, independently, from 1 to 4 carbon atoms.