Back to results
US 4,305,926 AGranted
Immobilization of Streptokinase
OwnerJohannes Everse, Kathleen E. Everse +1inventors
InventorsJohannes Everse, Kathleen E. Everse, Leo C. Mercer
Life of this patent
Estimating the term…
Abstract
The invention comprises the construction of an implantable device consisting of a clot lysing inhibitor immobilized onto a biocompatible polymer, and the method of regulation of blood clotting time, the prevention of blood clot formation, and the hydrolysis of existing blood clots with the use of said device. A method is also disclosed to prevent the growth of fibrous connective tissue on prosthetic devices.
Claims9
The process of control of blood clotting in a living mammal comprising:
- providing a clot-lysing initiator immobilized on a solid water insoluble non-colloidal substrate;
- and
- implanting said initiator supporting substrate in the body of said living mammal in contact with its body fluid.
A blood clotting control device comprising:
- a body fluid contacting means comprising, a solid water insoluble non-colloidal carrier substrate and immobilized clot lysing initiator carried by said solid carrier substrate, said solid carrier substrate and clot lysing initiator being adapted to be implanted in a living mammal in contact with the body fluids thereof.
Dependencies are inferred from the claim text.