US 4,304,938 A · Process for the preparation of 3-phenoxybenzenes

Abstract

3-Phenoxybenzene derivatives are prepared by a method which comprises the steps of(a) chlorinating benzaldehyde with chlorine gas in the presence of a hydrocarbon and a Lewis acid catalyst to obtain 3-chlorobenzaldehyde; (b) reacting the 3-chlorobenzaldehyde with ethylene glycol to obtain 2-(3-chlorophenyl)-1,3-dioxolane; (c) etherifying said dioxolane with an alkali phenolate to yield the intermediate 2-(3-phenoxyphenyl)-1,3-dioxolane and converting this intermediate to the corresponding aldehyde, cyanohydrin, sulfonic acid salt or oxime derivative.

Claims4

Dependent claims

A process for the preparation of a compound of the formula (V) ##STR10## which comprises the steps of:

(a) chlorinating benzaldehyde with chlorine gas in the presence of a chlorinated hydrocarbon and a Lewis acid catalyst to obtain 3-chloro-benzaldehyde;
(b) reacting the 3-chlorobenzaldehyde with ethylene glycol to yield a compound of the formula VIII:
##STR11## (c) etherifying the compound of formula VIII with an excess of alkali phenolate in the presence of Cu powder and Cu(I)Cl in phenol at a temperature of 105.degree. C. to 205.degree. C. to yield a compound of the formula VII:
##STR12## and:
(d) forming the desired product by reacting the compound of formula VII with a hydroxylammonium salt in the presence of water and a water-miscible organic solvent.

2 more elements

Dependencies are inferred from the claim text.

Process for the preparation of 3-phenoxybenzenes

Life of this patent

Process for the preparation of 3-phenoxybenzenes

Life of this patent

Abstract

Claims4