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US 4,304,931 AGranted
Biphenylhydroxypropionic acid derivatives
AssigneeThe Boots Company PLC
InventorsJohn S. Nicholson, John L. Turner
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Abstract
A process is disclosed for preparing arylpropionic acids of formula Ar--CH(CH.sub.3)--COOH, by reacting an aryl Grignard reagent with a metal pyruvate or with a pyruvamide, to form a hydroxy acid of formula Ar--C(OH)(CH.sub.3)--COOH or its amide, and converting the acid or amide to the product.
Claims1
2-(2-Fluoro-4-biphenylyl)-2-hydroxypropionic acid and its enantiomers.
Dependencies are inferred from the claim text.