Process for the preparation of cholesterol derivatives
AssigneeThe Green Cross Corporation
InventorsYoshio Arakawa, Atuyuki Takanabe, Yahiro Uemura, Satoshi Funakoshi, Daisuke Satoh
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Abstract
New organic dibasic acid half esters of 7-ketocholesterol and of 7-hydroxycholesterol represented by the general formula ##STR1## (wherein R.sub.1 is .dbd.O or --OH and R.sub.2 is a C.sub.1 -C.sub.5 alkylene group or a phenylene group) and physiologically acceptable salts thereof. These compounds are effective as an immunosuppressive or an anti-inflammatory agent.
Claims6
A method for preparing an organic dibasic acid half ester of 7-hydroxycholesterol, which comprises reducing the corresponding organic dibasic acid half ester of 7-ketocholesterol or a salt thereof in a solvent with a complex metal hydride.
Dependencies are inferred from the claim text.