S 31794/F-1 Nucleus
AssigneeEli Lilly and Company
InventorsBernard J. Abbott, David S. Fukuda
Life of this patent
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Abstract
S 31794/F-1 nucleus, which is prepared by enzymatic deacylation of antibiotic S 31794/F-1 using an enzyme produced by the Actinoplanaceae, preferably by Actinoplanes utahensis. S 31794/F-1 nucleus and salts thereof are useful intermediates for the preparation of new semi-synthetic antifungal agents.
Claims16
S 31794/F-1 nucleus of the formula ##STR22## and the acid addition salts thereof.
The method of deacylating antibiotic S 31794/F-1 which comprises exposing the antibiotic in an aqueous medium to an enzyme which deacylates and which is produced by a microorganism of the family Actinoplanaceae until substantial deacylation is accomplished.
Dependencies are inferred from the claim text.