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US 4,303,754 AGranted
Method for obtaining 7.beta. hydroxy steroids
OwnerIan Macdonaldinventor
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Abstract
Method of producing steroids having a 7.beta.-OH substituent which comprises subjecting a steroid having a B-ring structure of the formula, ##STR1## wherein X is OH; Y is H, and when taken together X and Y is oxo (O.dbd.), to the action of a microorganism of the genus Clostridium.
Claims6
A method for producing 7.beta.-OH substituted steroids which comprises subjecting a cholane steroid compound having a B-ring structure of the following formula:
- ##STR6## wherein X is OH, Y is H and when taken together X and Y is oxo (O.dbd.);
- to the action of a Clostridium absonum microorganism.
A method for producing ursodeoxycholic acid which comprises subjecting chenodeoxycholic acid to the action of the enzymes produced by the microorganism Clostridium absonum in a suitable medium.
Dependencies are inferred from the claim text.