Antiviral pyrazolopyrazines
AssigneeAbbott Laboratories
InventorsGerard Y. Paris, Mina D. Perlin, Andre G. Pernet, Nathan L. Shipkowitz
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Abstract
Certain 1-substituted-3-loweralkyl-5-(substituted)phenyl-6-aminopyrazolo[3,4-b]pyr azines are provided. They have useful activity as antivirals.
Claims12
A compound of the formula ##STR2## wherein R is loweralkyl, R' is hydrogen or loweralkyl, and R" is hydrogen, loweralkyl, loweralkyloxy, halogen or nitro.
A pharmaceutical composition in dosage form containing, as the active principle, an antivirally effective amount of a compound of the formula ##STR3## wherein R is loweralkyl, R' is hydrogen or loweralkyl, and R" is hydrogen, loweralkyl, loweralkyloxy, halogen or nitro, together with a pharmaceutically acceptable diluent.
A method to combat or prevent infections in a warm-blooded animal caused by vaccinia, rhino or influenza virus, comprising administering to said animal infected by such virus, an antivirally effective amount of a compound of the formula ##STR4## wherein R is loweralkyl, R' is hydrogen or loweralkyl, and R" is hydrogen, loweralkyl, loweralkyloxy, halogen or nitro.
Dependencies are inferred from the claim text.