1-Phenyl-2-aminoethanol derivatives

A method of treatment of an area of inflammation affecting the skin of a warm blooded animal which comprises topically administering to said area an effective amount of a compound of formula I, or a pharmaceutically acceptable acid-addition salt thereof:

• R.sup.1.CH(OH).CH.sub.2.NH.CR.sup.2 R.sup.3.A.sup.1.NH.[CO.Y.NH].sub.n Q I wherein R.sup.1 is a radical of the formula:
• ##STR3## in which W.sup.1 is a (2-12 C)alkanoyloxy, A.sup.2 is a direct bond or a methylene diradical, one of W.sup.2 and W.sup.3 is hydrogen, and the other of W.sup.2 and W.sup.3 is a (2-12 C)alkanoyloxy radical;
• or R.sup.1 is a phenyl, 2-chlorophenyl or 3,5-dichloro-4-aminophenyl radical;
• R.sup.2 and R.sup.3 are independently hydrogen or (1-4 C)alkyl radicals;
• A.sup.1 is a (1-4 C)alkylene diradical;
• Y is a (1-4 C)alkylene diradical optionally bearing a (1-4 C)alkyl or benzyl substituent;
• n is an integer from 1 to 4;
• and Q is a benzoyl, phenylacetyl or phenoxyacetyl radical optionally bearing a nuclear substituent selected from halogeno, (1-4 C)alkyl, (1-4 C)alkoxy and trifluoromethyl radicals;
• provided that when n is other than 1, Y is the individual diradicals of the formula [CO.Y.NH] may have the same or different values.