Process for the preparation of acyl cyanides
AssigneeBayer Aktiengesellschaft
InventorsKurt Findeisen, Karl-Heinz Linker
Life of this patent
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Abstract
Novel process for the preparation of a monomeric acyl cyanide of the general formula ##STR1## in which R represents optionally substituted alkyl with up to 8 carbon atoms, optionally substituted cycloalkyl with 3 to 12 carbon atoms, optionally substituted aryl or an optionally substituted 5-membered or 6-membered heterocyclic radical, which optionally can be fused with a benzene ring, which process comprises heating the corresponding dimeric acyl cyanide of the general formula ##STR2## in which R has the meaning stated above, to a temperature of from 50.degree. to 300.degree. C. in the presence of a compound having a basic reaction and rapidly removing the monomeric acyl cyanide (I) formed from the reaction mixture.
Claims36
A process for the preparation of a monomeric acyl cyanide of the formula ##STR14## in which R is optionally substituted alkyl of up to 8 carbon atoms and the substituents are selected from phenyl and naphthyl optionally substituted with alkyl, alkoxy, carbalkoxy and halogen;
- alkoxy or carboalkoxy of up to 4 carbon atoms in the alkoxy moiety;
- nitro;
- nitrile;
- and halogen;
- cycloalkyl which has 5 or 6 carbon atoms in the ring system and optionally substituted with at least one of alkyl, alkoxy or carboalkoxy with up to 4 carbon atoms, nitro, nitrile and halogen;
- phenyl or naphthyl optionally substituted with alkyl, alkoxy or carboalkoxy of up to 4 carbon atoms, nitro, nitrile and halogen;
- a heterocyclic radical of 5 to 6 ring atoms which can include 1 to 3 hetero ring atoms selected from oxygen, sulfur and nitrogen;
- a heterocyclic radical of 5 to 6 ring atoms fused to a benzene ring and which can include 1 to 3 hetero ring atoms selected from oxygen, sulfur and nitrogen;
- and
- a substituted heterocyclic radical of 5 or 6 ring atoms and 1 to 3 hetero atoms selected from oxygen, sulfur, nitrogen and at least one substituent selected from alkyl, alkoxy and carbalkoxy with, in each case, up to 4 carbon atoms, nitro, nitrile and halogen,
- which process comprises heating the corresponding dimeric acyl cyanide of the general formula ##STR15## in which R has the meaning stated above, to a temperature of from 50.degree. to 300.degree. C. in the presence of a basic compound and rapidly removing the monomeric acyl cyanide (I) formed from the reaction mixture.
Dependencies are inferred from the claim text.