Polyether ionophores as antiobesity and hypotriglyceridemic agents
AssigneeHoffmann-La Roche Inc.
InventorsKaren Comai, Ann Sullivan, John Westley
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Abstract
A method is disclosed for the use of polyether ionophores as antiobesity and hypotriglyceridemic agents in warm blooded animals by the administration to an animal in need of such treatment of a therapeutically effective dose of a polyether compound. Also disclosed are examples of such polyether compounds and methods for their preparation.
Claims12
A method of treating high triglyceride levels in warm blooded animals in need of such treatment which comprises orally administering to such warm blooded animals from 1 mg/kg/day to 300 mg/kg/day of polyether compound with ionophore activity sufficient to inhibit fatty acid synthesis or the activity of pancreatic lipase.
Dependencies are inferred from the claim text.