Pharmaceutical and dietary composition
AssigneeEfamol Limited
InventorDavid F. Horrobin
Life of this patent
Estimating the term…
Abstract
Compositions and use of .gamma.-linolenic acids and related materials alone or with zinc and or .beta.-lactam antibiotics to treat schizophrenia, obesity, menstrual disorders, skin disorders and other conditions, and .beta.-lactam antibiotics alone to treat schizophrenia.
Claims14
A pharmaceutical or dietary composition for administration to influence the balance of 1-series and 2-series PG's in the body in favor of 1-series PG's, said composition comprising:
- (a) .gamma.-linolenic acid or physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or physiologically functional derivative thereof present in an amount of from about 0.05 to 10 grams calculated as linolenic acid, and
- (b) form about 0.5 to 3 grams of a .beta.-lactam antiobiotic,
- alone or in an acceptable pharmaceutical or dietary vehicle.
A pharmaceutical or dietary composition for administration to influence the balance of 1-series and 2-series PG's in the body in favor of 1-series PG's, said composition comprising:
- (a) .gamma.-linolenic acid or physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or physiologically functional derivative thereof, said acid and/or derivative present in an amount of from about 0.05 to 10 grams calculated as linolenic acid,
- (b) a conjoint amount of about 2.5 to 800 mg of physiologically assimilable zinc calculated as the metal, and
- (c) a .beta.-lactam antibiotic,
- alone or in an acceptable pharmaceutical or dietary vehicle.
A method of treating schizophrenia comprising administering to a person suffering therefrom an effective amount of a pharmaceutical or dietary composition containing (a) .gamma.-linolenic acid or physiologically functional derivative thereof and/or dihomo-.gamma.-linolenic acid or physiologically functional derivative thereof, and (b) a conjoint amount of a further material influencing the 1-series/2-series PG balance in the body in favor of 1-series PGs, said composition being administered alone or in an acceptable pharmaceutical or dietary vehicle.
Dependencies are inferred from the claim text.