Vaccines for immunizing egg-laying birds against Egg Drop disease, preparation of said vaccines, and method of use of said vaccines
AssigneeAkzo N.V.
InventorWilliam Baxendale
Life of this patent
Estimating the term…
Abstract
There are disclosed novel vaccines for immunizing egg-laying birds against Egg Drop disease, a group of novel viruses (generically called EDS 76 virus) used in the preparation of such vaccines, and methods for immunizing egg-laying birds against Egg Drop disease or syndrome.
Claims13
A process for the preparation of a live, unattenuated vaccine that protects egg-laying birds against the Egg Drop disease comprising
- growing an EDS 76 virus selected from the group consisting of virus EDS 76 (VLO 10110/AV1) on cell tissue culture and
- harvesting the infected culture material selected from the group consisting of tissue culture fluids, the cells, and mixtures thereof.
A process for the preparation of a live, unattenuated vaccine that protects egg-laying birds against the Egg Drop disease comprising
- growing an EDS 76 virus selected from the group consisting of virus EDS 76 (VLO 10110/AV1) in embryonated eggs and
- harvesting any of the embryos, the membranes, and allantoic fluids.
A process for the preparation of a live, attenuated vaccine that protects egg-laying birds against the Egg Drop disease comprising
- adapting an EDS 76 virus selected from the group consisting of virus EDS 76 (VLO 10110/AV1) to an avian tissue cell-containing culture and
- undertaking a plurality of passages of said virus in said culture to multiply said virus.
A process for the preparation of an inactivated vaccine that protects egg-laying birds against the Egg Drop disease comprising
- inactivating an EDS 76 virus selected from the group consisting of virus EDS 76 (VLO 10110/AV1) with an inactivating agent selected from the group consisting of an enzyme, an organic solvent, formaldehyde, .beta.-propiolactone, and mixtures of an enzyme and an organic solvent.
A vaccine effective against Egg Drop disease comprising an EDS 76 virus selected from the group consisting of virus EDS 76 (VLO 10110/AV1) in an unattenuated form.
A vaccine effective against Egg Drop disease comprising an EDS 76 virus selected from the group consisting of virus EDS 76 (VLO 10110/AV1) in an attenuated form.
A vaccine effective against Egg Drop disease comprising an EDS 76 virus selected from the group consisting of virus EDS 76 (VLO 10110/AV1) in an inactivated form.
Dependencies are inferred from the claim text.