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US 4,302,438 AGranted
Antigen, antiserum and immunoassay for theophylline
AssigneeByk Gulden Lomberg Chemische Fabrik GmbH
InventorKarl Zech
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Abstract
By injecting a host animal with a member of a particular group of antigens [a theophylline-(7)-alkanecarboxylic acid covalently bonded to an immunogenic carrier (IGC) via the carboxyl group], antibodies, advantageously employed in determining small amounts of theophylline in biological liquids by immunoassay methods, are obtained.
Claims40
An antigen in the structure of which a haptene of the formula
- T--(CH.sub.2).sub.n --COOH
- wherein
- T is theophylline-(7) and
- n is an integer from 2 to 4, inclusive,
- is covalently bonded via the carbonyl group to an immunogenic carrier.
2 more elements
Dependencies are inferred from the claim text.