Blood bags having an insert member
AssigneeBaxter Travenol Laboratories, Inc.
InventorHenry W. Collins
Life of this patent
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Abstract
A blood bag or other container which is made of a flexible, hemocompatible, sterilizable plastic material free of blood-extractable plasticizer. The blood bag contains an insert member which comprises a non-toxic, sterilizable plastic formulation which contains from 5 to 70 percent by weight of a blood-extractable plasticizer selected from the group consisting of the dioctylphthalates and dioctyladipates. Such a blood bag is capable of reducing the plasma hemoglobin in stored blood, when compared with similar blood bags without the insert member.
Claims19
A blood bag which comprises a flexible, translucent container equipped with access tubing and sealed access ports, said blood bag comprising:
- a flexible, hemocompatible, sterilizable plastic material, essentially free of blood-extractable plasticizer, said blood bag containing an insert member, said insert member comprising a non-toxic, sterilizable plastic formulation which contains from 5 to 70 percent by weight of a blood-extractable plasticizer selected from the group consisting of the dioctylphthalates and dioctyladipates.
A blood container which comprises a hemo-compatible, sterilizable material, essentially free of blood-extractable plasticizer, said blood container containing an insert member, said insert member comprising a non-toxic, sterilizable plastic formulation which contains sufficient material selected from the group consisting of dioctylphthalates and dioctyladipates to cause blood stored in said blood bag for 21 days to exhibit a reduced plasma hemoglobin content when compared with blood stored in a comparable blood container free of said material.
A blood container which comprises a hemo-compatible, sterilizable material, essentially free of blood-extractable plasticizer, said blood container containing an insert member, said insert member comprising a non-toxic, sterilizable, plastic formulation which contains sufficient antihemolytic agent, capable of leaching from said plastic formulation, to cause blood stored in said blood bag for 21 days to exhibit a reduced plasma hemoglobin content when compared with blood stored in a comparable blood container free of said antihemolytic agent.
The method of storing blood which comprises placing said blood for a period of days into a flexible, hemocompatible, sterilizable plastic material, essentially free of blood-extractable plasticizer, said blood bag containing an insert member, said insert member comprising a non-toxic, sterilizable, plastic formulation which contains a blood extractable antihemolytic agent in sufficient quantity to cause blood stored in said blood bag for 21 days to exhibit a reduced plasma hemoglobin content when compared with blood stored in a comparable blood container free of said material.
The method of storing blood which comprises placing blood for a period of days in a blood bag made of a flexible, hemocompatible, sterilizable plastic material, essentially free of blood-extractable plasticizer, said blood bag containing an insert member, said insert member comprising a non-toxic, sterilizable plastic formulation which contains from five to 70 percent by weight of an antihemolytic material selected from the group consisting of the dioctylphthalates and dioctyladipates.
Dependencies are inferred from the claim text.