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US 4,301,249 AGranted
High titer production of hepatitis A virus
AssigneeMerck & Co., Inc.
InventorsHenry Z. Markus, William J. McAleer
Life of this patent
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Abstract
Hepatitis A virus (HAV) is produced in high titer from tissue cultures grown on a hollow fiber capillary unit.
Claims9
A method for enhancing the yield of HAV in in vitro cell culture which comprises growing the virus in a susceptible cell culture planted on a hollow fiber capillary unit under conditions which permit viral replication.
Dependencies are inferred from the claim text.