Fermentation process for making rachelmycin
AssigneeBristol-Myers Company
InventorsDonald E. Nettleton, Jr., James A. Bush, William T. Bradner
Life of this patent
Estimating the term…
Abstract
A known antibiotic substance designated herein as rachelmycin is produced by fermentation of Streptomyces sp. strain C-329, variant 70 (ATCC 31128) or Streptomyces anandii subsp. arraffinosus strain C-22, 437 (ATCC 31431). Rachelmycin exhibits both antibiotic and antitumor properties.
Claims4
A process for producing rachelmycin which comprises cultivating a rachelmycin-producing strain of Streptomyces sp. having the identifying characteristics of ATCC 31128 or Streptomyces anandii subsp. arraffinosus having the identifying characteristics of ATCC 31431, or a mutant thereof, in an aqueous nutrient medium under submerged aerobic conditions until a substantial amount of rachelmycin is produced by said organism in said culture medium.
Dependencies are inferred from the claim text.